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Fastest Humans
Relative to the planet Earth, the fastest speed humans have achieved was 24,791 miles per hour (39,914 km/hr), by the Apollo 10 astronauts, on their return trip from the moon in 1969.
But the universe is much bigger than the Earth-Moon system, and everything moves. If the Sun is taken as a fixed point, then all the humans on Earth are moving at about 66,660 miles per hour (107,320 km/hr) as the Earth follows its orbit.
If the center of the Milky Way galaxy is a fixed point, then the solar system is moving at about 500,000 miles per hour (800,000 km/hr) in its orbit around the galaxy.
From an even broader reference frame, our entire local group of galaxies is moving at about one million miles per hour toward another galaxy group called Virgo Cluster.

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-Toast-
"It takes a lot of brains to enjoy satire, humor and wit - but none to be offended by them." -- Johnny Hart ("BC", cartoonist, 2000)
"Analyzing humor is like dissecting a frog: Nobody really enjoys it and the frog generally dies as a result." -- E. B. White